Stuart McDonald

Stuart McDonald is Professor of Gastrointestinal Biology and Group Leader whose research focuses on stem cell niches and clonal expansion in Barrett’s oesophagus, stomach and breast cancer.

His primary research interests include:

• Stem Cell Biology
• Cancer Evolution
• Gastrointestinal Cancers
• Barrett's Oesophagus
• Colorectal Cancer
• Breast Cancer

Publications spanning 2011–2023 demonstrate consistent investigation into cellular dynamics using lineage tracing and molecular profiling, revealing stem cell organization in liver, colon, and breast tissues with implications for cancer development.

Major research funding includes:

• Cancer Research UK Grand Challenge award (2019, £20m share) for 'STORMing Cancer: STrOmal ReprograMing'
• Cancer Research UK Foundation programme award (2016–2021, £1.2m) for Barrett’s oesophagus evolution studies

Additional roles: Director of The Haemochromatosis Society and member of NCRI Upper GI group. Leads research within the Centre for Cancer Evolution.