Srinjan Basu

Dr. Srinjan Basu serves as a Lecturer in the Department of Life Sciences at Imperial College London and is an Affiliated Principal Investigator at the Cambridge Stem Cell Institute. His research bridges physics, chemistry, and biology through advanced imaging methodologies.

His laboratory pioneers single-cell and single-molecule imaging approaches to investigate chromatin dynamics during stem cell differentiation. Key interests include genome architecture regulation, chromatin-binding protein kinetics, and the role of structural misregulation in cancer progression. The Basu Lab develops cutting-edge techniques including 3D single-molecule tracking, live-cell single-molecule FRET, and machine-learning algorithms for motion classification.

Research trends across publications reveal a consistent focus on visualizing molecular processes at unprecedented resolution. His work integrates biophysics with stem cell biology, emphasizing single-cell heterogeneity in genome architecture and protein-chromatin interactions. Methodological innovations dominate his output, with increasing computational integration in recent studies.

As former chair of the equality, diversity and inclusion community at the Cambridge Stem Cell Institute, Dr. Basu actively promotes inclusive research practices. His laboratory fosters interdisciplinary collaboration between mathematicians, physicists, chemists, and biologists while training next-generation researchers in data-driven biology.

The Basu Lab operates within Imperial College London's Department of Life Sciences at the Sir Alexander Fleming Building, developing novel imaging platforms to study chromatin regulators in mammalian embryo development and stem cell fate transitions.