جست‌وجوی استاد و پژوهشگر

Sriram Subramaniamمشاهده پروفایل

استاد

• cryo-electron microscopy
• structural biology
• drug-design
• +۴ مورد دیگر

Sriram Subramaniam is a Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia (UBC) and holds the Gobind Khorana Canada Excellence Research Chair in Precision Cancer Drug Design. His research leverages cryo-electron microscopy (cryo-EM) to advance structural biology and drug design, focusing on protein dynamics and therapeutic target identification. Education: PhD in Physical Chemistry (1987) from Stanford University; MSc in Chemistry (1981) from Indian Institute of Technology, Kanpur. Subramaniam's interdisciplinary work combines cryo-EM with computational tools and molecular biology to study protein structures at atomic resolution. His lab has pioneered cryo-EM applications in precision medicine, including mapping small molecule drugs on patient-specific cancer mutants. Recent publications (2024-2022) highlight his contributions to understanding SARS-CoV-2 immune evasion, structural mechanisms of ATPases, and AI integration in structural biology. His research spans viral entry mechanisms, CRISPR systems, and neurodegenerative disease pathways. Scientific Awards: Gobind Khorana Canada Excellence Research Chair NIH Director’s Award for Scientific Excellence Fellow of the Biophysical Society Breakthrough Prize nomination Based at the Djavad Mowafaghian Center for Brain Health, Subramaniam leads the Program in Cryo-EM Guided Drug Design, contributing to over 177 peer-reviewed publications with a career h-index of 58 and citations exceeding 12,340.

Björn Corziliusمشاهده پروفایل

استاد

• Solid-state NMR Spectroscopy
• Dynamic Nuclear Polarization (DNP)
• Biomolecular Chemistry
• +۳ مورد دیگر

Prof. Dr. Björn Corzilius is a University Professor (W2) of Physical Chemistry at the University of Rostock, Germany, leading the Corzilius group. His research focuses on solid-state NMR spectroscopy, dynamic nuclear polarization (DNP), and applications in biomolecules and materials. He holds affiliations with the Leibniz Institute for Catalysis (LIKAT) and serves on multiple academic boards, including the transregional Collaborative Research Center TRR 386 and the journal Magnetic Resonance . Education: 1999: Studies of Chemistry, TU Darmstadt 2005: Diploma in Physical Chemistry (TU Darmstadt) 2008: Ph.D. in Physical Chemistry (TU Darmstadt) Research Interests: Solid-state NMR, DNP for sensitivity enhancement, paramagnetic metal ions, biomolecular dynamics, and method development. His work bridges theoretical and experimental approaches to advance structural and functional studies of complex systems like proteins, nucleic acids, and catalytic materials. Recent Article Trends: Focus on DNP applications in biomolecular interfaces, novel polarizing agents (e.g., Gd(III) complexes), and methodological advancements like serial polarization transfer and electron-decoupled DNP. Contributions span inorganic chemistry, materials science, and biophysical systems. Awards: Emmy Noether Fellowship (2012) Felix Bloch Lecture (2016) Regitze M. Vold Memorial Prize (2017) Best Ph.D. Supervision (2018) Grants & Labs: Principal Investigator of the Emmy Noether Group (2013–2019), now leading the DNP research team at the University of Rostock. Collaborates closely with LIKAT on catalytic and materials projects. His group actively develops open-access publishing platforms like Magnetic Resonance and hosts international conferences. Labs/Teams: The Corzilius group at the Institute of Chemistry (Rostock) specializes in NMR method development and applications. Associated with LIKAT for interdisciplinary catalysis research.

Gary Pielakمشاهده پروفایل

استاد

• Protein Biophysics
• In-Cell NMR Spectroscopy
• Macromolecular Crowding
• +۳ مورد دیگر

Gary Pielak is a Kenan Distinguished Professor of Chemistry, Biochemistry, and Biophysics at the University of North Carolina at Chapel Hill, with a joint appointment in the School of Medicine. His research focuses on high-resolution protein NMR studies in living cells and the biophysics of tardigrade desiccation-tolerance proteins, bridging structural biology and molecular biophysics. Education: BS in Chemistry from Bradley University (1977), PhD in Biochemistry from Washington State University (1983), Postdoc at the University of British Columbia (1983-1986), Postdoc at Oxford University (1986-1988). Research Interests center on understanding protein structure, stability, and function in physiologically relevant environments. Key areas include: In-Cell NMR: Quantifying protein behavior in living cells using advanced NMR techniques. Macromolecular Crowding: Studying synthetic polymers and proteins as crowding agents to mimic cellular environments. Tardigrade Biology: Exploring desiccation-tolerance mechanisms in intrinsically disordered proteins from water bears. Recent Publications highlight interdisciplinary trends, combining AI-driven stability prediction, solid-state NMR for dry protein analysis, and molecular glass/gel applications for preservation. His Scientific Awards include: NIH Pioneer Award DuPont and Morrow Young Faculty Awards Multiple UNC Mentorship Awards Mentorship is a cornerstone, with a focus on training graduate students and advancing NMR methodologies. His group employs Research Methods : 19F, 1H, 15N, and 13C NMR Circular Dichroism and Calorimetry Protein Expression in E. coli

Bradley D. Olsenمشاهده پروفایل

استاد

• Polymer Science
• Materials Engineering
• Soft Condensed Matter Physics
• +۴ مورد دیگر

Bradley D. Olsen is a full professor in the Department of Chemical Engineering at the Massachusetts Institute of Technology (MIT), where he leads research at the intersection of polymer science, soft matter physics, and bioengineering. His work focuses on designing materials for critical applications in biotechnology, hemostasis, and sustainable polymer development while advancing fundamental understanding of polymer network mechanics and self-assembly. Education: Ph.D. in Chemical Engineering, University of California Berkeley (2007) S.B. in Chemical Engineering, Massachusetts Institute of Technology (2003) Olsen's research spans protein-based materials, block copolymer phase behavior, and mechanochemical hydrogels. He has pioneered methods for quantifying polymer network topology, developing hemostatic nanoparticles, and creating bio-inspired materials for selective biomolecular transport and medical applications. His recent publications emphasize data-driven approaches to polymer characterization and educational outreach in materials science. Scientific Awards: American Physical Society (APS) Fellow (2023) Fulbright Amazonia Scholar (2023) Alexander and I. Michael Kasser Chair in Chemical Engineering (2021) ACS Macro Letters Young Investigator Award (2021) MIT Committed to Caring Honor (2019) AIChE Owens Corning Early Career Award (2019) APS Dillon Medal (2018) Kavli Emerging Leader in Chemistry (2017) ACS Polymer Division Fellow (2016) Camille Dreyfus-Teacher Scholar (2015) Alfred P. Sloan Research Fellow (2014) NSF Career Grant (2013) NIH Postdoctoral Fellowship (2008-2009) Hertz Fellow (2003-2007) Barry M. Goldwater Scholarship (2002) Olsen has received significant grant support including NSF Career (2013) and AFOSR (2012) awards. His teaching activities include innovative international outreach like the 2025 soccer-themed science camp in Brazil. The Olsen Group at MIT explores advanced materials with applications ranging from trauma care to sustainable polymers.

Jacob Bukoskiمشاهده پروفایل

استادیار

• Forest Carbon Sequestration
• Carbon Markets
• Biogeochemistry
• +۳ مورد دیگر

Jacob Bukoski is Assistant Professor and Director of the Forests and Climate Change graduate certificate at Oregon State University's College of Forestry. His research examines forest carbon dynamics, climate mitigation, and international forestry. Education includes: PhD in Environmental Science from UC Berkeley MS in Environmental Science from Yale University BA in Environmental Studies from UNC Chapel Hill Research focuses on carbon accumulation in forests, mangrove conservation, and climate policy integration. Teaches interdisciplinary courses on social-ecological systems and forest carbon analysis. Recent publications quantify carbon storage in global plantations and mangrove ecosystems. Current projects investigate albedo impacts on reforestation protocols and coastal conservation synergies. Directs graduate studies in Forests and Climate Change.

• Computational Modelling of Neural Networks
• Biophysical Modelling of EEG/MEG
• Diffusion Tractography
• +۲ مورد دیگر

Professor Thomas R. Knösche is a Group Leader at the Methods and Development Group Brain Networks within the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig, Germany. His research focuses on computational modeling of neural networks, biophysical modeling of EEG/MEG data, diffusion tractography, and the neurocognition of language and music. He holds a professorship at the institute and leads research initiatives in brain networks and neuroimaging methodologies. His work bridges theoretical neuroscience with practical applications in understanding brain function through advanced computational techniques. Contact information includes his office phone (+49 341 9940-2619) and lab address: Stephanstraße 1A, 04103 Leipzig, Saxony, Germany.

Jason Rittمشاهده پروفایل

دانشیار

• Computational Neuroscience
• Data Science
• Neuroengineering
• +۳ مورد دیگر

Jason Ritt is an Associate Professor of Brain Science (Research) and Scientific Director of Quantitative Neuroscience at the Robert J. and Nancy D. Carney Institute for Brain Science, Brown University. He holds affiliations with the Data Science Institute and collaborates across disciplines on quantitative research methods. Education : B.S., M.A., and Ph.D. in Neuroscience from Boston University (1997–2003). Research : Focuses on neural processing during active sensing and neuroengineering for neurostimulation. Combines electrophysiology, optogenetics, and theoretical approaches in rodent models. Develops closed-loop systems for studying sensory neural prosthetics and brain-machine interfaces. Key areas include synaptic diversity, neurocontrol algorithms, and sensory restoration. Teaching : Instructs NEUR 2100 NeuroPracticum, integrating hands-on neuroscience research training.

• Machine Learning
• Computational Neuroscience
• Artificial Intelligence
• +۷ مورد دیگر

Aapo Hyvärinen is a Professor of Computer Science at the University of Helsinki , affiliated with the Helsinki Institute for Information Technology and the Helsinki Probabilistic Machine Learning Lab . He previously held the position of Professor of Machine Learning at the Gatsby Computational Neuroscience Unit, University College London (2016-2019). Education : Undergraduate Mathematics at University of Helsinki, Vienna, and Paris; Ph.D. in Information Science from Helsinki University of Technology (1997) His research focuses on machine learning and computational neuroscience , particularly: Independent Component Analysis (ICA) Natural Image Statistics Causal Representation Learning Neural Signal Processing Applications to brain imaging (MEG, CryoEM) Recent publications emphasize causal discovery , identifiable machine learning , and nonlinear ICA . Key projects include: VETURI (AI for health) DIGIMIND (AI in mental health) CIFAR grants (2022-2025) Scientific awards : Highly Cited Researcher (2010) He serves as Action Editor for the Journal of Machine Learning Research and Neural Computation , and has held Area Chair roles at NeurIPS, ICML, ICLR, AISTATS, and UAI conferences. His work bridges theoretical machine learning with neuroscience and philosophical implications of artificial intelligence .

Waldemar Kolanusمشاهده پروفایل

استاد

• Molecular Immunology
• Cell Signaling
• Signal Transduction Pathways
• +۴ مورد دیگر

Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788

• Inverse problems and reconstruction
• Neuroimaging
• Quantitative MRI
• +۱ مورد دیگر

Daan Christiaens is a tenure track lecturer at KU Leuven's Faculty of Medicine and Faculty of Engineering Sciences. He is affiliated with the Department of Electrical Engineering (ESAT) and Department of Imaging & Pathology, serving as a member of the Medical Imaging Division and the KU Leuven Brain Institute (LBI). His academic responsibilities include membership in the Faculty Councils of Engineering Sciences and Medicine. His research focuses on: Inverse problems in medical imaging reconstruction Neuroimaging techniques for brain analysis Advanced quantitative MRI methodologies Diffusion-weighted imaging for microstructural assessment Dr. Christiaens' recent publications (2023-2025) demonstrate a consistent focus on diffusion MRI innovations, including novel reconstruction algorithms, neonatal brain development mapping, and clinical applications for neurodegenerative disorders. Key technical themes include motion correction, multi-shell modeling, and AI-enhanced image processing, while clinical applications span Alzheimer's disease, cerebral palsy, and autism research. He leads significant research projects including: MRI reconstruction with dynamic field monitoring (2024-2028) Compressed sensing for microstructure imaging (2022-2026) Neonatal diffusion MRI network connectivity analysis (2024-2028) As a core developer of the MRtrix3 software framework for medical image processing, he contributes to essential tools in neuroimaging research.

• Biophysics
• Membrane Proteins
• Structural Biology
• +۳ مورد دیگر

Dr. Lukas Frey is a Researcher at ETH Zurich, affiliated with the Chair of Physical Chemistry and the Institute of Molecular Physical Sciences (IMPS). His work focuses on biophysical studies of membrane proteins, lipid dynamics, and protein aggregation mechanisms. Key research areas include structural biology of ion channels, NMR spectroscopy of membrane proteins in nanodiscs, and the role of lipid environments in modulating protein dynamics. Frey employs advanced techniques like mass photometry and solid-state NMR to investigate molecular mechanisms in biological systems. His recent studies address amyloid fibril formation, pH-dependent α-synuclein polymorphism, and cholesterol-mediated modulation of membrane protein behavior. Based at the HCI F 228 facility in Zurich, Frey collaborates on projects involving lipid bilayer environments, ion channel function, and the structural basis of protein aggregation. His email is lukas.frey@phys.chem.ethz.ch, and he holds an ORCID identifier 0000-0002-1052-1104. Research contributions span from fundamental biophysical insights to methodological advancements in membrane protein analysis.

Michael Lampsonمشاهده پروفایل

استاد

• Cell and Developmental Biology
• Evolution
• Cell biology of meiotic drive
• +۷ مورد دیگر

Michael Lampson is Professor of Biology at the University of Pennsylvania's School of Arts and Sciences, with secondary appointments in the Department of Cell and Developmental Biology. He serves as faculty in the Cell and Molecular Biology (CAMB) and Biochemistry and Molecular Biophysics (BMB) Graduate Groups, and is affiliated with the American Society for Cell Biology (ASCB). Ph.D., Cornell University, Weill Medical College, 2002 AB, Harvard College, 1994 Dr. Lampson's research program focuses on fundamental mechanisms of chromosome biology, with particular emphasis on cell division, centromere inheritance, and meiotic drive. His lab investigates how selfish genetic elements can violate Mendel's First Law through meiotic drive, the stability of centromere chromatin through the germline, and the role of repetitive satellite DNA in chromosome segregation. Using innovative approaches including mouse model systems, optogenetic tools, and biochemical techniques, his work bridges cell biology, genetics, and evolutionary biology to address questions with implications for reproductive biology, cancer, and genetic inheritance. Analysis of Dr. Lampson's recent publications reveals a strong focus on the intersection of centromere biology, meiotic drive, and chromosome segregation mechanisms. His work increasingly incorporates computational approaches alongside experimental systems to study evolutionary aspects of centromere function. The research demonstrates consistent innovation in methodology, particularly in developing optogenetic tools for precise manipulation of cellular processes. Key themes include the role of satellite DNA variation, mechanisms of non-Mendelian inheritance, and the stability of chromatin structures through cell division and development. Searle Scholar Award American Association for the Advancement of Science (AAAS) fellow Dr. Lampson's research is supported by multiple NIH grants including from NIGMS, NHGRI, NICHD, and NCI, as well as University of Pennsylvania funding sources including the University Research Foundation, Abramson Cancer Center, and several specialized research centers. He collaborates extensively with researchers across disciplines, including Ben Black (Biochemistry), Dennis Discher (Chemical Engineering), Dave Chenoweth (Chemistry), and Roger Greenberg (Cancer Biology), reflecting the interdisciplinary nature of his work. His lab has trained numerous graduate students and postdocs who have gone on to successful careers in academia and industry. The Lampson Lab maintains state-of-the-art facilities for cell biological, genetic, and biochemical research, with specialized equipment for live-cell imaging, optogenetic manipulation, and mouse genetics. The lab fosters a collaborative environment that bridges molecular, cellular, and evolutionary perspectives on chromosome biology.

Aditi Dasمشاهده پروفایل

استاد

• Biochemistry and Chemical biology of Lipids
• Mechanism of Membrane proteins in Nanodiscs
• Enzymology of metalloproteins
• +۵ مورد دیگر

Aditi Das is a Full Professor in the School of Chemistry and Biochemistry at the Georgia Institute of Technology, College of Sciences. She leads the Das Laboratory, which focuses on the biochemistry and chemical biology of lipids, particularly studying cytochrome P450 enzymes and their role in lipid metabolism, endocannabinoid systems, and inflammatory pathways. Her educational background includes: B.Sc. in Chemistry from St. Stephen's College M.Sc. in Chemistry from Indian Institute of Technology, Kanpur (I.I.T) Ph.D. in Chemistry from Princeton University Postdoctoral research at Northwestern University (NSF-NSEC fellow) and Beckman Institute for Advanced Science and Technology, University of Illinois UC Professor Das's research interests center around understanding the physiological role of lipids in sustaining homeostasis and their implications in disease states such as neurodegenerative disorders, cancer, and cardiovascular diseases. Her laboratory specializes in: Enzymology of cytochrome P450s, particularly CYP2J2 epoxygenase Metabolism of ω-3 and ω-6 fatty acids and their derivatives Minor cannabinoid metabolism by cytochrome P450 enzymes Discovery of novel anti-inflammatory lipid metabolites and endocannabinoids Mechanistic studies of membrane proteins using nanodisc technology Her work bridges biochemistry, chemical biology, and pharmacology to uncover novel therapeutic targets related to lipid signaling pathways. Analysis of Professor Das's recent publications (2023-2025) reveals a strong focus on cannabinoid metabolism by cytochrome P450 enzymes, with particular emphasis on how these metabolic processes generate bioactive compounds that interact with the endocannabinoid system. Her research increasingly explores the therapeutic potential of omega-3 derived endocannabinoid epoxides in inflammatory and neurodegenerative conditions. The use of nanodisc technology for studying membrane proteins in near-native environments remains a consistent methodological thread throughout her work, enabling detailed mechanistic insights into enzyme function. Professor Das has received numerous prestigious awards recognizing her research excellence and teaching: 2024 NIH Outstanding Researcher Award (MIRA R35) for established investigators 2024 Vasser Woolley Faculty Fellowship 2023 Plenary Lecture at the International Society of the Study of Xenobiotics (ISSX) 2021 E.L.R. Stokstad Award 2019-2021 List of Teachers Ranked as Excellent 2019 Eicosanoid Research Foundation Young Investigator Award 2019 Zoetis Research Excellence Award 2019 Mary Swartz Rose Young Investigator Award 2015 National Scientist Development Award from the American Heart Association 2022 El Sohly Award from the American Chemical Society Professor Das actively mentors a diverse group of students and postdoctoral researchers, with several former lab members now holding faculty positions or working at prestigious institutions. Her laboratory has secured significant funding from NIH, NSF, and other sources to support research on lipid metabolism, cannabinoid pharmacology, and membrane protein biochemistry. Notable grants include an NIH R35 Outstanding Investigator Award (MIRA), an NIH R21 grant from NIDA, and multiple collaborative grants with other research groups. The Das Laboratory operates within the Petit Institute of Bioengineering and Biosciences (IBB) at Georgia Tech, utilizing state-of-the-art facilities for biochemical and biophysical studies. The lab specializes in nanodisc technology to study membrane proteins in near-native environments, with particular expertise in cytochrome P450 enzymes and their interactions with lipid substrates. Recent work has expanded into collaborative projects involving lipidomics, structural biology, and translational applications of lipid signaling research.

Graham Dobereinerمشاهده پروفایل

دانشیار

• Homogeneous Catalysis
• Organometallic Chemistry
• Synthetic Chemistry
• +۲ مورد دیگر

Graham Dobereiner is an Associate Professor and Robert L. Smith Early Career Professor in the Department of Chemistry at Temple University's College of Science and Technology. He received his Ph.D. from Yale University (2011) and completed postdoctoral research at MIT (2012-2014) after earning his B.S. from Brandeis University (2007). His research group develops novel homogeneous transition metal catalysts for synthetic chemistry applications spanning fine chemicals manufacturing, petrochemical processing, and drug discovery. The work integrates organometallic chemistry principles, combining organic molecular diversity with inorganic compound reactivity. Research areas include catalytic isomerization, oxidative synthesis, ligand design, and mechanistic studies of transition metal complexes. Analysis of his recent publications demonstrates strong emphasis on reaction mechanism elucidation, catalyst design for stereoselective transformations (particularly Z-selective isomerizations), and development of novel catalytic systems for sustainable synthesis. His group employs computational and experimental approaches to advance synthetic methodology.

• Biomedical Signal and Image Processing
• Cardiovascular and Neural Modeling
• Physiologically-interpretable Artificial Intelligence systems
• +۵ مورد دیگر

Gaetano Valenza is an Associate Professor of Bioengineering at the University of Pisa, Italy, where he leads the Neuro-Cardiovascular Intelligence Lab at the Enrico Piaggio Research Centre. He holds affiliations with the Neuroscience Statistics Research Laboratory at MIT and has served as a Research Fellow at Harvard Medical School and Massachusetts General Hospital. His academic work spans bioengineering, computational physiology, and affective computing. His research focuses on statistical and nonlinear biomedical signal and image processing , cardiovascular and neural modeling , and physiologically interpretable artificial intelligence . He develops wearable systems for physiological monitoring, with applications in autonomic nervous system assessment, brain-heart interactions, and mental health. His work has led to novel metrics such as the Sympathetic and Parasympathetic activity indices derived from ECG. The 15 most recent publications reflect a consistent trend in brain-heart interplay , complexity analysis of physiological signals , explainable AI in healthcare , and virtual reality applications in mental health . His work integrates advanced signal processing, nonlinear dynamics, and machine learning to decode emotional and cognitive states from physiological data. Dr. Valenza is a Senior Member of IEEE and serves on several technical committees. He is an active editorial leader, currently serving as Associate Editor for IEEE-EMBC , Plos One , Complexity , and Scientific Reports , and has guest-edited special issues in Philosophical Transactions of the Royal Society A and IEEE Journal of Biomedical and Health Informatics . He has led or participated in numerous international research projects, including FP7 and H2020 initiatives such as NEVERMIND and EXPERIENCE. He teaches courses in Biostatistics, Probability & Biostatistics, and Advanced Image Processing at the University of Pisa. As lab head and project coordinator, he leads a multidisciplinary team working on neuro-cardiovascular intelligence, wearable systems, and AI-driven mental health interventions.