Sridevi Challa

Sridevi Challa serves as Assistant Professor in the Department of Obstetrics and Gynecology-Gynecologic Oncology at the University of Chicago, conducting research at the intersection of cancer biology and molecular biochemistry.

Her primary research focuses on:

• NAD+ metabolism in gynecological malignancies
• ADP-ribosylation pathways (PARylation and MARylation)
• Cytosolic signaling mechanisms in tumor progression
• Therapeutic targeting of post-translational modifications

Recent publications (2021-2024) demonstrate a cohesive research trajectory exploring how NAD+-dependent processes and ADP-ribosylation regulate gynecological cancer biology, with emphasis on identifying novel therapeutic vulnerabilities through biochemical pathway analysis.

Her collaborative networks include connections with researchers in protein modification (Lin, Hening; Moellering, Raymond) and gynecologic oncology specialists (Lengyel, Ernst; Lindau, Stacy) within the University of Chicago medical ecosystem.