Dan Huang

Dan Huang is an Associate Professor at UT Southwestern Medical Center, affiliated with the Cecil H. and Ida Green Center for Reproductive Biology Sciences and the Department of Obstetrics and Gynecology. She holds a joint position in the Department of Obstetrics and Gynecology. Her career includes roles as a cardiologist at Wuhan Union Hospital, a Visiting Assistant Professor at UT Southwestern (2017–2021), and promotion to Associate Professor in 2012. She earned her M.D. and Ph.D. in Medicine from Tongji Medical College, Huazhong University of Science and Technology, China, in 2009.

Education:

• M.D. and Ph.D. in Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), China (2009)
• Postdoctoral/Visiting positions at UT Southwestern Medical Center (2017–2021)

Research Interests:

Her research focuses on molecular mechanisms of histone modifications, chromatin regulation, and ADP-ribosylation processes. Key areas include:

• PARP enzyme functions and their roles in disease
• Interplay between histone post-translational modifications
• Links between epigenetic mechanisms and cardiovascular/metabolic disorders and cancers

Publications Overview:

Her work emphasizes PARP enzymes, ADP-ribosylation in disease pathways, and epigenetic regulation. Recent studies investigate molecular mechanisms in cancer, metabolic diseases, and liver toxicity, often involving protein modifications and signaling pathways. Themes include therapeutic targeting of PARP1 and PARP-mediated processes.

Advising & Grants:

No advisees are listed in the provided materials. Grant information is not explicitly detailed here.

Labs & Teams:

Affiliated with the Green Center for Reproductive Biology Sciences and collaborates with interdisciplinary teams at UT Southwestern, focusing on translational epigenetics and disease mechanisms.