Andreas G. Ladurner

Prof. Dr. Andreas G. Ladurner is a faculty member at the Faculty of Medicine, Ludwig-Maximilian University of Munich, where he leads the Department of Physiological Chemistry. His research focuses on the molecular mechanisms of chromatin plasticity, particularly through post-translational modifications like ADP-ribosylation and acetylation, and their interplay with cellular metabolites.

• Discovered the first cellular receptor for glucose metabolites
• Elucidated PARP1's role in chromatin remodeling
• Defined macrodomain proteins' function in ADP-ribosylation

His work bridges structural biology, epigenetics, and metabolism, with significant implications for cancer and metabolic diseases. Recent publications highlight his group's contributions to DNA damage response and chromatin dynamics. Funded by the BioM m4 Award, his lab investigates:

• Regulation of transcription factors by metabolites
• Mechanistic insights into the histone chaperone FACT
• Molecular dissection of ADP-ribosylation signaling