معرفی
Skyler Jackman is an Assistant Scientist at the Vollum Institute and holds a faculty appointment in the Department of Behavioral Neuroscience within the School of Medicine at Oregon Health & Science University (OHSU). He leads the Jackman Lab, which investigates synaptic plasticity mechanisms using electrophysiology, calcium imaging, and optogenetics. His research focuses on identifying calcium sensors like synaptotagmins that modulate neural processing and behavior.
Education
- Ph.D. in Physics (2009), University of California, Berkeley
- B.A. in Physics, University of California, Berkeley
- Postdoctoral training at Harvard Medical School
Research Focus
Jackman's work centers on short-term synaptic plasticity (STP), particularly facilitation mediated by synaptotagmin 7 (Syt7). His lab studies how STP influences sensory processing, cognition, and neuropsychiatric disorders (e.g., autism, schizophrenia) using knockout models and in vivo techniques. Key research areas include presynaptic calcium dynamics, vesicle recycling, and neural circuit modulation.
Publications
His 12 most recent articles (2014–2024) predominantly explore synaptic transmission mechanisms, calcium sensor functions (especially synaptotagmins 3/7), and optogenetic innovations. Publications in Nature, Neuron, and Cell Reports demonstrate a consistent focus on molecular neuroscience and neural circuit analysis.
Lab Operations
The Jackman Lab recruits postdocs and graduate students for projects involving in vivo recordings, behavioral assays, and calcium imaging. It emphasizes interdisciplinary approaches to link synaptic mechanisms to brain function and disease.
