Shrinivas Krishna

Shrinivas Krishna is an Assistant Professor at Northwestern University with a joint appointment in the Department of Chemical and Biological Engineering, and courtesy affiliations with the Departments of Engineering Sciences and Applied Mathematics and Cell and Developmental Biology. His research integrates computational biology, biophysics, and machine learning to investigate biomolecular condensates, genome organization, and transcriptional regulation at the molecular and cellular scales.

Research Interests

The Shrinivas Lab focuses on:

• Deciphering the physics-driven mechanisms of nuclear condensate organization and RNA binding
• Developing machine learning frameworks for intrinsically disordered protein design
• Exploring statistical physics of soft and active matter systems
• Investigating the role of phase separation in gene regulation and disease

His work leverages collaborations with the Center for Synthetic Biology, NU Medical School, and national research networks.

Publications

Recent studies include analyses of multicomponent condensate dynamics (2024), nuclear condensate regulation (2023), and foundational work on phase separation principles (2017–2021). Key themes span RNA-protein interactions, intracellular compartmentalization, and computational approaches to biological complexity.