Shrinivas Bishu

Dr. Shrinivas Bishu is a Clinical Assistant Professor of Internal Medicine at the University of Michigan Medical School, with dual appointments as H Marvin Pollard Collegiate Professor of Gastroenterology IV and active clinical/educational leadership roles.

• Education: BA (University of Pennsylvania, 1998), MD (University of Nebraska Medical Center, 2003), Postdoctoral Immunology Training (NIH 2009, University of Pittsburgh 2023)
• Training: Internal Medicine Residency (University of Kentucky), Gastroenterology Fellowship (University of Pittsburgh Medical Center)

His research focuses on immunological mechanisms in Inflammatory Bowel Disease (IBD), particularly:

• Role of tissue-resident memory T-cells (TRM) in intestinal inflammation and repair
• IL-15 signaling in Th17 TRM pathogenesis
• Microbiota-disease interactions
• Immune therapy development
• Protective feedback loops in gut inflammation

Recent publications examine:

• PCR diagnostics for IBD flares
• Virtual reality brain-gut treatments
• Sulfidogenic microbes in Crohn's disease
• C-reactive protein as surgical risk biomarker
• Postoperative outcomes with JAK inhibitors

Awards:

• Multiple fellow-elected teaching awards recognizing clinical/educational mentorship

Clinical Leadership: Specialized care for IBD patients with inadequate response to anti-TNF therapies, and educational leadership roles including:

• GI Fellowship Associate Program Director
• Director of IBD Education
• Director of Internal Medicine GI outpatient rotation
• Director of GI Grand Rounds