Shinya Hanashima

Dr. Shinya Hanashima is a researcher at the Structural Glycobiology Team, RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, part of RIKEN Global Research Cluster in Wako, Saitama, Japan. His work focuses on the structural and functional aspects of protein-carbohydrate interactions, particularly in the context of immune recognition and host-pathogen interactions.

Dr. Hanashima's research interests center on glycobiology and structural biology, with specific focus on lectin-glycan interactions. His work examines how human soluble lectins like ZG16p recognize and bind to microbial glycans, particularly mycobacterial phosphatidylinositol mannosides (PIMs). His research employs advanced techniques including glycan microarray analysis, NMR spectroscopy, and molecular docking simulations to elucidate the precise molecular mechanisms of these interactions. This work has implications for understanding host immune responses to bacterial pathogens and potentially developing new therapeutic approaches.

His publication record shows consistent contributions to high-impact journals including ChemBioChem, Journal of Biological Chemistry, and Molecular Cell, demonstrating expertise in both structural and functional aspects of glycobiology. His collaborative work with international teams, including researchers from Max Planck Institute and Imperial College London, highlights the interdisciplinary nature of his research.