معرفی
Sandra Wolin is a Senior Investigator and Chief of the RNA Biology Laboratory at the National Cancer Institute (NCI), part of the Center for Cancer Research. Previously, she held the rank of Professor Emeritus of Cell Biology at Yale School of Medicine. She earned her MD and PhD from Yale University and completed postdoctoral training at the University of California, San Francisco.
Her research focuses on RNA biology, including RNA surveillance pathways, noncoding RNAs, and their roles in autoimmune diseases and cancer. Key contributions include discovering the Ro60 autoantigen's role in RNA degradation and its implications for lupus and Sjögren’s syndrome. Her work also explores how RNA damage contributes to cancer and the efficacy of chemotherapeutics.
- Awards: Fellow of the American Academy of Microbiology (2014), AAAS (2013), Ellison Foundation Senior Scholar (2006), and member of the National Academy of Sciences (2024).
- Lab Leadership: Head of the NCI RNA Biology Initiative and Section on Noncoding RNAs and RNPs.
- Education: A.B. from Princeton University, MD/PhD from Yale.
Her articles highlight interdisciplinary approaches to RNA biology, linking basic research to disease mechanisms. Notable studies include the design of RNA-based therapies for ALS/FTD and elucidating the role of commensal bacteria in lupus pathogenesis.
