معرفی
Ryan MacLeod is a Clinical Fellow in the Department of Internal Medicine, specializing in Endocrinology and Metabolism at Yale School of Medicine. He completed his MD and PhD in Interdisciplinary Biomedical Sciences at the University of Arkansas for Medical Sciences (2021) and holds a BS in Biological Sciences from the University of Arkansas (2014). He is part of the ABIM Physician-Scientist Research Pathway and is board certified in Internal Medicine (2024). His research focuses on bone biology, including molecular mechanisms of bone mass regulation, gene editing via CRISPR, and age-related bone disorders. He is affiliated with the Section of Endocrinology and Metabolism, collaborating with researchers like Dr. O’Brien CA on projects involving osteocytes and bone remodeling.
Education:
- BS Biological Sciences, University of Arkansas (2014)
- MD/PhD Interdisciplinary Biomedical Sciences, University of Arkansas for Medical Sciences (2021)
Research Interests: MacLeod’s work investigates bone biology through studies of autophagy, genetic regulation (e.g., Tnfsf11), and CRISPR applications. Key areas include osteocyte RANKL’s role in cortical bone loss and molecular pathways driving bone resorption. His research bridges clinical endocrinology with advanced genetic techniques.
Articles Trends: Publications (2019–2024) highlight bone metabolism, CRISPR applications, and molecular mechanisms of bone disorders. Recent work explores dual diagnoses in infectious diseases and clinical guidelines for denosumab discontinuation.
Advising/Grants: While no specific grants are listed, his participation in the Physician-Scientist Pathway supports clinical and research training. He aims to integrate clinical endocrinology practice with bone research.
Labs/Teams: Affiliated with the Section of Endocrinology and Metabolism at Yale School of Medicine, collaborating with teams focused on translational bone research.
