معرفی
Ruhan Deniz TOPUZ serves as an Assistant Professor in the Department of Medical Pharmacology at Trakya University Faculty of Medicine, specializing in neuropsychopharmacology and endocannabinoid system research. With a medical degree (2005) and PhD in Medical Pharmacology (2015) from the same institution, their work bridges clinical medicine and molecular neuroscience.
Education includes:
- Bachelor of Medicine, Trakya University Faculty of Medicine (2005)
- Doctorate in Medical Pharmacology, Trakya University (2015)
Research focuses on endocannabinoid signaling in stress responses, pain mechanisms, and cognitive disorders. Key interests include TRPV1 receptor interactions with analgesics, neuroinflammation in psychiatric conditions, and epigenetic regulation of memory. Recent work explores serum biomarkers for bipolar disorder and novel interventions for autism spectrum disorders using natural compounds.
Analysis of 15 most recent publications reveals strong emphasis on:
- Endocannabinoid system modulation in psychiatric and neurological conditions
- Ischemic conditioning techniques for pain and tissue repair
- Natural compounds (fucoxanthin, ginsenosides) as neuroprotectants
- Molecular mechanisms linking stress to cognitive impairment
As primary supervisor for multiple Master's theses, TOPUZ mentors research on fear conditioning, autism models, and neurotensin signaling. Current projects investigate remote ischemic conditioning for neuropathic pain and serum biomarkers in stress models. Active in ethical oversight as Clinical Research Ethics Committee member since 2023, with h-index 6 reflecting impactful contributions to pharmacological neuroscience.