معرفی
Rudi Fasan is an Adjunct Professor of Chemistry at the University of Rochester, affiliated with the School of Arts & Sciences and the Department of Chemistry. He holds a PhD from the University of Zurich, Switzerland (2005). His research focuses on bioorganic chemistry, chemical biology, and biomolecular engineering, integrating organic chemistry, molecular biology, and molecular evolution to develop novel chemo-biosynthetic tools. Key interests include macrocyclic organo-peptide hybrids (MOrPHs) for targeting protein-protein interactions (PPIs) and engineered enzymes for C—H functionalization.
Education: PhD in Chemistry, University of Zurich (2005).
Research interests span:
- Design of MOrPHs for PPI modulation
- Engineering P450 and myoglobin-based catalysts for C—H activation
- Chemoenzymatic synthesis of complex molecules
- Protein engineering for enhanced enzyme stability and selectivity
His recent work highlights advancements in enantioselective cyclopropanation, P450-derived biocatalysts, and structure-activity profiling of antileukemic agents. No formal student advisees are listed, but the Fasan Lab trains interdisciplinary researchers at the chemistry-biology interface.
Labs/Teams: Directs the Fasan Research Group, focusing on biocatalytic methodologies and molecular recognition platforms.
