معرفی
Ronald Kluger is a Professor of Organic and Biological Chemistry at the University of Toronto's Department of Chemistry. His research focuses on protein modification, particularly hemoglobin, to develop acellular oxygen carriers for medical applications. Kluger's work includes site-specific cross-linking of hemoglobin using 'click chemistry' and investigating mechanisms of carbon dioxide release in decarboxylation reactions. His group also explores thiamin-derived intermediates and lanthanide-catalyzed reactions in water.
- Affiliations: University of Toronto, Department of Chemistry; Collaborations with Toronto General Hospital's surgery department.
- Labs: Laboratories in Davenport Building 450/451.
Research Interests: Hemoglobin modification for oxygen therapeutics, decarboxylation mechanisms, protein-protein coupling, and biomimetic synthesis. Key projects include creating non-vasoactive oxygen carriers from cross-linked hemoglobin and studying carbonic acid intermediates in decarboxylation.
Grants & Awards: Not explicitly listed, but sustained research output indicates sustained funding. Collaborations include industry partnerships (e.g., lung transplant research).
