معرفی
Roberta Brambilla is an Associate Professor of Neurological Surgery at the University of Miami Miller School of Medicine, affiliated with The Miami Project to Cure Paralysis. She holds dual roles in research and teaching, focusing on neuroinflammation and neuroimmune interactions in neurological disorders like multiple sclerosis, spinal cord injury, and traumatic brain injury. Her research emphasizes glial cell biology, TNF signaling pathways, and cholesterol metabolism in CNS diseases.
Educations:
- Ph.D. in Pharmacology/Neuroscience, University of Milan, 2000
- M.S. in Pharmacology, University of Milan, 1995
- B.S. in Pharmacology/Neuroscience, University of Milan, 1993
Research Interests: Dr. Brambilla investigates neuroinflammation's role in neurodegenerative disorders, particularly TNF's dual functions in membrane-bound and soluble forms. Her work explores TNFR2 signaling in glial cells, oligodendrocyte dysfunction in primary progressive MS, and cholesterol's role in neuroprotection. She also develops novel transgenic mouse models and deep learning tools for CNS injury analysis.
Awards:
- Eureka Institute Course in Translational Medicine (University of Miami)
- International Society for Neuroimmunology Travel Awards (multiple)
- First Prize, Italian Society of Pharmacology (1995)
Grants & Labs: Dr. Brambilla leads a lab focusing on TNF biology, neurodegeneration, and translational therapies. Her work includes collaborations on anti-ASC monoclonal antibodies (IC100) and selective TNFR2 agonists for MS therapy. She is affiliated with The Miami Project's interdisciplinary research teams.
