معرفی
Robert W. Keane, Ph.D., is a Professor in the Departments of Physiology and Biophysics, Neurological Surgery, and Microbiology and Immunology at the University of Miami's Miller School of Medicine. He leads research on innate immune responses in the central nervous system (CNS), particularly focusing on inflammasome activation in neurodegenerative diseases and trauma. His laboratory discovered the role of ASC in inflammasome pathways and developed IC100, a therapeutic antibody targeting ASC, supported by an NIH STTR grant. Dr. Keane co-founded InflamaCORE, LLC, to advance treatments for CNS inflammation and neurodegenerative disorders.
Education:
- Bachelor’s in Biology: SUNY College at Buffalo
- MS and Ph.D. in Genetics: University of California, Davis
- Postdoctoral Fellowship: MIT (Molecular Biology & Neuroscience), funded by Leukemia Society of America
Research Interests:
- Innate immune signaling in CNS injury and neurodegeneration
- Inflammasome regulation and therapeutic targeting
- Exosome-mediated inflammatory pathways
- Biomarker discovery for CNS diseases
Teaching: Over 39 years of medical and graduate education, including course director roles in Neuroscience, Neurophysiology, and Developmental Neuroscience. Developed innovative curricula and clinical modules integrating basic science with clinical practice.
Grants & Awards: NIH STTR grant for IC100 drug development, Leukemia Society postdoctoral fellowship, and patents on inflammasome modulation strategies. His work has been featured in startup ventures and translational research collaborations with industry.
