معرفی
Rhian Touyz is a Professor in the Department of Medicine at McGill University's Faculty of Medicine and Health Sciences. She serves as a Senior Scientist at the Research Institute of the McGill University Health Centre (RI-MUHC) at the Glen site, where she leads research within the Lifelong Cardiovascular Health Research Program at the Center for Translational Biology.
Dr. Touyz's research focuses on elucidating the molecular and cellular processes that lead to vessel damage in hypertension. Her work specifically investigates reactive oxygen species, signaling molecules, hormones, and enzymes that cause damage to cells in the vascular wall. As evidenced by her extensive publication record, her laboratory has made significant contributions to understanding oxidative stress mechanisms in vascular biology, particularly related to NOX enzymes, ion channels, and signaling pathways in hypertension.
Analysis of Dr. Touyz's recent publications (2019-2025) reveals a consistent research trajectory focused on molecular mechanisms of vascular dysfunction in hypertension. Her work spans multiple sub-disciplines including oxidative stress biology, ion channel physiology, vascular signaling pathways, and the intersection of cardiovascular disease with other conditions like obesity, cancer therapies, and viral infections. A significant portion of her recent work examines NOX enzymes (particularly NOX4 and NOX5) and their role in redox signaling in vascular cells. Her research has important clinical implications for understanding hypertension pathophysiology and developing novel therapeutic approaches.
Dr. Touyz actively contributes to clinical guidelines and public health initiatives related to hypertension management, as demonstrated by her publications in CMAJ addressing Canadian hypertension practices. She also has a growing body of work in cardio-oncology, examining vascular complications of cancer therapies. Her research demonstrates strong translational potential, bridging basic molecular mechanisms with clinical applications in cardiovascular disease prevention and treatment.
