معرفی
Reza Kalhor is an Associate Professor at Johns Hopkins University School of Medicine, with joint appointments in the Department of Biomedical Engineering, Molecular Biology and Genetics, and Neuroscience. He is a Core Member of the Center for Epigenetics, where his research integrates synthetic biology, genomics, and computational methods to map and engineer cell fate during development.
- Department: Biomedical Engineering
- School: School of Medicine
- Institution: Johns Hopkins University
- Research Center: Center for Epigenetics
His research focuses on developmental neuroscience, lineage tracing, and synthetic biology, particularly using CRISPR-based technologies to record cellular histories. His lab develops molecular tools such as homing CRISPR barcodes and spatial transcriptomics methods to reconstruct developmental trajectories with high resolution.
The recent publications of Dr. Kalhor span areas including in vivo lineage recording, spatial genomics, cancer evolution, and genome architecture. His work frequently appears in high-impact journals like Science, Nature, and Cell, reflecting a strong trend toward integrating molecular recording with developmental and disease modeling.
Dr. Kalhor is actively involved in mentoring graduate students through the Biomedical Engineering Program, Neuroscience Training Program, and the Biochemistry, Cellular and Molecular Biology (BCMB) Graduate Program. He collaborates on major initiatives such as the 4D Nucleome Project and has contributed to foundational protocols in CRISPR-based lineage tracing.
- Graduate Programs: Biomedical Engineering, Neuroscience, BCMB
- Lab Focus: Synthetic lineage recording, spatial transcriptomics, developmental mapping
- Collaborations: 4D Nucleome Project, Church Lab, Garza Lab
