معرفی
Alexej Abyzov is an Adjunct Assistant Professor at the Yale School of Medicine’s Child Study Center. His research focuses on genomic mosaicism, neurodevelopmental disorders, and the application of cutting-edge genomic technologies to study brain disorders. Key areas include somatic mutations in neuropsychiatric diseases, single-cell transcriptomics, and developmental neurobiology. He collaborates extensively with teams investigating schizophrenia, autism, and Tourette disorder.
Education: PhD in Biomedical Science, Northeastern University (2008).
Research Focus: Dr. Abyzov’s work integrates genomic analysis, computational biology, and neurodevelopmental studies. His lab uses single-cell RNA sequencing, spatial transcriptomics, and CRISPR-based tools to uncover mechanisms underlying brain disorders. Recent studies highlight somatic mosaicism in psychiatric conditions and the role of enhancer activity in neurodevelopment.
Publications: His research spans high-impact journals like Science, Nature Communications, and Biological Psychiatry, with a focus on genomic analysis of brain tissues and cell-lineage tracing. Themes include interneuron loss in Tourette’s, chromosomal rearrangements in developmental disorders, and cross-ancestry brain gene regulation.
Labs/Teams: The Abyzov Lab at Yale focuses on computational genomics and neurodevelopmental systems. Collaborations include the Brain Somatic Mosaicism Network and the BrainSpan consortium.
