معرفی
Rekha Rai is a Senior Research Scientist in the Department of Laboratory Medicine at Yale School of Medicine, Yale University. She earned her PhD (1998), MS (1993), and BS (1991) from Banaras Hindu University. Her research investigates DNA damage detection mechanisms, DNA lesion repair pathways, and the role of telomeres in cancer initiation and aging, with a focus on telomere maintenance and genome stability.
Her publications predominantly explore telomere biology, structural analyses of telomeric complexes, and repair pathway mechanisms. Recent work highlights the regulation of homology-directed telomere repair, nuclear envelope interactions, and replication machinery involvement in telomere maintenance. Key themes include:
- Mechanisms suppressing RAD51-dependent recombination at telomeres
- Telomere-nuclear envelope cooperation in genome stability
- Structural insights into shelterin complex proteins (TRF2, RAP1, POT1-TPP1)
- Dysfunctional telomere repair choices mediated by phosphorylation signals
No awards, students, or grant details are mentioned in the provided text. She collaborates extensively with researchers including Sandy Chang and maintains an active publication record in high-impact journals.
