معرفی
Raimund Dutzler is a Full Professor of Biochemistry at the University of Zurich's Department of Biochemistry (since 2009), and Head of Department since August 2024. His research focuses on elucidating the structural and functional mechanisms of transmembrane ion and lipid transport proteins using cryo-electron microscopy, X-ray crystallography, and electrophysiology. Key projects include studies on ClC chloride channels, TMEM16 lipid scramblases, LRRC8 volume-regulated anion channels, and SLC11/NRAMP metal transporters.
Education: Ph.D. in Biophysics (University of Basel, 1998), postdoctoral training at Rockefeller University (2003). Teaching roles span courses in Biochemistry (e.g., BCH 100, BCH 630) and Human Biology (HUB 240a).
Research Interests: Multidisciplinary approaches to ion and lipid transporters/channels, structural basis of transport selectivity, pharmacological targeting of transport proteins, and disease-related mechanisms (e.g., cystic fibrosis, iron overload disorders). Recent work includes structural characterization of heteromeric LRRC8 channels and inhibition mechanisms of TMEM16A.
Scientific Awards: ERC Advanced Investigator Grant (2013), EMBO Young Investigator Award (2006). Active grants include NCCR Structural Biology and Swiss National Science Foundation funding.
Lab Team: Includes Postdocs (Melanie Arndt, Anastasiia Sukalskaia), PhD Students (Panagiotis Kreouzis, Elena Lehmann, etc.), and administrative support.
