Qiushi Sun

Qiushi Sun is an Associate Research Scientist at Yale University’s Yale School of Medicine, primarily affiliated with the Department of Endocrinology. His research focuses on metabolic networks, immunometabolism, and the application of advanced metabolomics techniques such as stable isotope-resolved metabolomics (SIRM). He investigates metabolic pathways in diseases like cancer, neurodegeneration, and inflammatory conditions, with a particular emphasis on environmental and toxicological impacts on metabolism.

Dr. Sun’s work integrates cutting-edge analytical chemistry methods, including ion chromatography and ultra-high-resolution mass spectrometry, to map metabolic networks and study drug resistance mechanisms. His contributions include elucidating the role of inosine in T-cell function under glucose deprivation and exploring how air pollution disrupts hepatic metabolism. He collaborates with the Kibbey Lab, advancing interdisciplinary research at the intersection of metabolism, immunology, and environmental health.

Key areas of research include metabolic profiling of oncological disorders (e.g., multiple myeloma), redox signaling in neurons, and the metabolic consequences of gene mutations in neurodegenerative diseases. His methodologies have been applied to 3D tumor spheroid models and non-invasive mouse studies, enhancing our understanding of disease mechanisms and potential therapeutic targets.

Dr. Sun’s expertise spans metabolic pathway analysis, stable isotope tracing, and the development of novel analytical tools for metabolomics. His findings have implications for personalized medicine, environmental health policies, and immunotherapy strategies.