معرفی
Professor Peter McCaffery holds a Personal Chair at the University of Aberdeen's Institute of Medical Sciences within the School of Medicine, Medical Sciences and Nutrition. His research focuses on retinoic acid's role in the brain, particularly neurodegenerative diseases like Alzheimer's and ALS. He leads a lab exploring vitamin A's neuroprotective potential, synthetic retinoid development, and hypothalamic regulation of retinoid homeostasis. McCaffery has supervised numerous students and postdocs, including Azita Kouchmeshky (neurodegenerative therapeutics) and Thabat Khatib (neuroplasticity). He teaches courses in biochemistry and molecular pharmacology. Key collaborators include Bill Blaner (Columbia University) and Andy Whiting (Durham University). His work is funded by Wellcome Trust, BBSRC, and others. McCaffery has published over 90 articles with an h-index of 54, emphasizing retinoid signaling in cognition, cannabinoid interactions, and translational neuroscience. His lab developed the RAR-M DC645 compound for ALS treatment, demonstrating neuroprotective effects in motor neuron models.
