Peter C. Gaines

Peter C. Gaines is Professor and Department Chair of Biological Sciences at the Kennedy College of Sciences, University of Massachusetts Lowell. His research focuses on molecular signaling pathways in blood cell differentiation and neutrophil development, with implications for innate immunity and myelogenous leukemias.

• Ph.D. in Molecular Genetics, Yale University (1996)
• B.S. in Biology, University of Vermont (1985)

Research interests include:

• Nuclear Envelope Proteins: Lamin B receptor's role in myeloid differentiation and cholesterol biosynthesis
• Transcriptional Regulation: GABP, PU.1, and C/EBPε interactions in granulocyte nuclear maturation
• Nanotoxicology: Impact of engineered nanomaterials on immune cell function

Recent publications emphasize neutrophil differentiation mechanisms, lamin isoform dynamics, and nano-bio interactions in occupational health and biomedical devices.

Scientific awards:

• NIH Mentored Research Scientist K01 Award
• NIH National Research Service Awards (Postdoctoral, Predoctoral)
• Multiple teaching excellence awards at UMass Lowell

Active in NIH-funded research on nuclear envelope regulation and nanomaterial safety, with patent-related hydrogel innovations for ophthalmic drug delivery.