Pernilla Wikström

Pernilla Wikström is a Professor at the Department of Medical Biosciences, Section of Pathology at Umeå University, Sweden. She also serves as Assistant Director at the Wallenberg Centre for Molecular Medicine at Umeå University (WCMM). Her research activities are centered at Umeå universitet, with offices located at By 6M, vån 2, Sjukhusområdet (901 85 Umeå) for her primary position and at Umeå universitet, 901 87 Umeå for her WCMM role.

Dr. Wikström's research focuses on biomarker discovery for aggressive prostate cancer, with particular emphasis on early detection methods that can distinguish potentially lethal forms at curable stages. Her lab employs advanced proteomics, metabolomics, and genomics techniques to analyze blood and tissue samples, aiming to develop sensitive diagnostic tools and identify novel therapeutic targets. The research group investigates molecular subtypes of prostate cancer, bone metastasis mechanisms, and the relationship between androgen receptor activity and tumor progression.

Analysis of her recent publications reveals a strong focus on molecular classification of prostate cancer subtypes, with particular attention to bone metastasis and treatment resistance mechanisms. Her work increasingly integrates multi-omics approaches to identify clinically actionable biomarkers, with significant contributions to understanding how tumor microenvironment, immune response, and metabolic profiles relate to disease progression and therapeutic outcomes.

• Recipient of research funding through the Swedish Cancer Society
• Involved in Umeå University's New Cancer Fund initiative (30 million SEK total for ten projects)

Dr. Wikström leads the Pernilla Wikström Lab, which currently oversees the SPRINTR project (September 2023-February 2027) and previously directed research on 'Biomarkers for aggressive prostate cancer' (2007-2010). Her research group maintains extensive collaborations with other prostate cancer researchers, as evidenced by her numerous co-authored publications across multiple high-impact journals.

The Pernilla Wikström Lab at Umeå University represents a significant research hub for prostate cancer biomarker discovery, combining molecular techniques with clinical applications to improve patient outcomes. The lab's work bridges basic science and clinical practice, with findings directly informing potential diagnostic tools and therapeutic strategies for aggressive prostate cancer forms.