Marjolein van Driel

Dr. Marjolein van Driel is an Assistant Professor in the Department of Internal Medicine at Erasmus MC, where she conducts cutting-edge research at the intersection of oncology and bone metabolism. Her work primarily focuses on bone metastasis, vitamin D signaling, and tumor-bone microenvironment interactions in cancers such as non-small cell lung cancer and prostate cancer.

Her research interests span Bone Metastasis, Vitamin D Signaling, Osteoblast Biology, RANKL Pathway, Extracellular Vesicles, and Cancer-Induced Bone Disease. She investigates how molecular signals from tumors affect bone remodeling and how endocrine factors like vitamin D modulate this crosstalk.

The recent trend in her publications shows a strong emphasis on identifying biomarkers for skeletal-related events in lung cancer patients, particularly those with EGFR mutations. Her studies integrate clinical data with molecular analysis to explore RANKL-expressing extracellular vesicles and their potential as non-invasive indicators of bone metastasis progression and treatment response.

Dr. van Driel actively collaborates with leading researchers in oncology and bone biology, including Drs. van Leeuwen, Dingemans, and Hendriks. Her collaborative network reflects a multidisciplinary approach combining internal medicine, molecular oncology, and metabolic bone disease research.