معرفی
Per Øyvind Enger is a Professor at the Department of Biomedicine, Faculty of Medicine, University of Bergen, Norway. He is actively affiliated with the Neurology Clinic at Haukeland University Hospital and leads research in translational cancer and vascular research, particularly focusing on glioblastoma and brain metastases.
- Institution: University of Bergen
- Department: Department of Biomedicine
- Faculty: Faculty of Medicine
- Clinical Affiliation: Haukeland University Hospital
His research interests center on understanding tumor-stroma interactions, cancer stem cells, and developing novel therapeutic strategies for malignant brain tumors. He investigates molecular mechanisms of tumor invasion, radiosensitization using repurposed drugs like sulfasalazine, and targeting metabolic pathways such as the xCT-glutathione axis. His work integrates preclinical models with clinical translation, including Gamma Knife radiosurgery and biomarker development.
The publication trends reflect a strong focus on neuro-oncology, with recurring themes in tumor microenvironment, targeted therapy, drug repurposing, and combination treatments involving radiation, chemotherapy, and immunotherapy. Recent works emphasize the role of glial and immune cells in tumor progression and treatment response.
He has supervised multiple Master’s and doctoral students, contributing to training the next generation of researchers. His collaborative projects span chemistry, imaging, and clinical neurosurgery.
- Research Groups: Translational Cancer Research, Translational Cancer and Vascular Research
- Grants: Involved in preclinical studies on sulfasalazine, dactolisib, and buparlisib for glioblastoma (as part of doctoral work he supervised)
His lab utilizes advanced models including patient-derived xenografts, dynamic MRI, and molecular targeting strategies. The team focuses on bridging experimental findings with clinical applications, particularly in radiosurgery and treatment response assessment.
