معرفی
Per Nilsson serves as Principal Researcher and Docent at Karolinska Institute's Department of Neurobiology, Care Sciences and Society. His laboratory investigates the role of autophagy in Aβ metabolism and neurodegeneration in Alzheimer's disease.
His research focuses on Alzheimer's disease pathogenesis, with particular emphasis on amyloid-β metabolism, autophagy mechanisms, synaptic dysfunction, and sex-specific differences in neurodegeneration. His work employs advanced transgenic mouse models including App-NL-G-F and App NL-F strains to dissect early pathological events.
Analysis of his recent publications reveals consistent themes across multiple high-impact journals: molecular mechanisms of amyloid processing, autophagy-lysosomal dysfunction, synaptic and network impairments, and exploration of therapeutic interventions targeting protein homeostasis. His work frequently bridges basic molecular mechanisms with translational applications.
Dr. Nilsson maintains active collaborations across neuroscience disciplines, contributing to major reviews on Alzheimer's modeling and autophagy guidelines. His laboratory participates in international research networks focused on dementia mechanisms and intervention strategies.
