معرفی
Niels Reinders serves as a Research Fellow at Vrije Universiteit Amsterdam's Faculty of Science, holding dual research associate appointments within Amsterdam Neuroscience across the Cellular & Molecular Mechanisms and Neurodegeneration divisions. His work centers on molecular pathways in neurodegenerative disorders through the Molecular and Cellular Neurobiology research group.
His research specializes in Alzheimer's disease mechanisms, focusing on amyloid-β-induced synaptic pathology, AMPA receptor dynamics, and endocytic processes in neurodegeneration. He employs molecular neuroscience approaches to investigate how amyloid-β triggers synaptic removal of GluA3-containing receptors, linking cellular dysfunction to cognitive decline through biochemical and genetic analyses of transgenic models.
His 2025 Journal of Neuroscience publication demonstrates amyloid-β's role in synaptic deficits via GluA3-AMPA receptor removal, representing current work at the intersection of molecular neurobiology and neurodegenerative disease mechanisms. This research contributes to understanding early synaptic alterations in Alzheimer's pathology.
Dr. Reinders operates within VU Amsterdam's Molecular and Cellular Neurobiology laboratory infrastructure and collaborates extensively through Amsterdam Neuroscience's cross-institutional research networks focused on cellular mechanisms of neurodegeneration.
