معرفی
Professor Per Bullough is the Harrison Chair in Structural Biology at the University of Sheffield, School of Biosciences, and holds a professorial position in the Department of Molecular Biology and Biotechnology. His career spans over three decades, with roles including BBSRC Research Development Fellow (2002-2005) and Lecturer (1995-2001). He earned a PhD in Structural Biology from the University of Cambridge (1985-1988) and a B.Sc. in Physics and Biology from King's College London (1982-1985).
- Research Focus: Structural biology of cellular interfaces, electron cryomicroscopy, and X-ray crystallography. Key interests include pathogenic bacteria (e.g., Clostridium spp., Bacillus spp.), bacteriophage mechanisms, and spore architecture.
His research employs cutting-edge techniques like Cryo-EM and crystallography to study bacterial cell walls, S-layers, and spore surfaces. Recent work includes molecular insights into C. difficile S-layer assembly and the structural basis of bacteriophage infection.
- Publications: Over 50 peer-reviewed articles, with recent contributions focusing on actin filament structures, spore surface architecture, and toxin mechanisms. Notable works include studies on Bacillus anthracis spore exosporium and Gram-positive cell wall dynamics.
Teaching: Leads undergraduate courses on membrane protein structure (MBB309), physical methods for biological structure analysis (MBB302), and genetics (MBB162).
Research Group: Active in mentoring PhD students and postdocs in structural microbiology and pathogen biology.
