معرفی
Pawel Grzechnik is a Lecturer at the School of Biological Sciences, University of Manchester, where he investigates molecular mechanisms of transcription and RNA processing in eukaryotic cells. His lab focuses on proteins interacting with RNA Polymerase II, particularly CREPT and RPRD1A, in contexts of cancer, neurodevelopment, and viral infections.
- PhD in Biology from University of Warsaw
- Postdoctoral work at Sir William Dunn School of Pathology, University of Oxford
- Established his lab at University of Birmingham via Sir Henry Dale Fellowship
His research spans RNA biology, transcriptional regulation, and co-transcriptional RNA processing, with projects on:
- Oncoproteins in transcription cycles
- Prader-Willi Syndrome pathogenesis via non-coding RNAs
- RNA processing under cellular stress
Notable trends in his publications include transcription termination, RNA capping, and disease-linked gene expression. Awards highlight his expertise:
- 2023 Roche Innovation Centre award
- 2020–2023 Prader-Willi research grant
- 2016–2022 Sir Henry Dale Fellowship
- EMBO and Wellcome Trust funding
He actively supervises PhD students and supports external funding applications (e.g., China Scholarship Council). Collaborations span omics approaches, single-cell RNA analysis, and plant development projects.
