معرفی
Professor Paula Booth is the Daniell Chair of Chemistry at King's College London, leading an interdisciplinary research group focusing on membrane protein folding and synthetic biology. She holds academic positions in the Department of Chemistry and the Francis Crick Institute. Her work bridges Chemistry and Life Sciences, investigating membrane protein biogenesis, lipid interactions, and synthetic biomembranes.
- Affiliations: King's College London (Department of Chemistry, Faculty of Natural, Mathematical & Engineering Sciences), Francis Crick Institute
- Advisory Roles: UK Biochemical Society, US Protein Society, Rosalind Franklin Next Generation Chemistry Board, BBSRC Appointments Board, and multiple funding panels (BBSRC, EPSRC, ERC, Wellcome Trust)
Research Interests
Her research explores the biosynthetic folding of membrane proteins, lipid regulation of membrane function, and construction of synthetic membrane modules. Key areas include:
- Co-translational folding mechanisms
- Lipid modulation of protein function
- Artificial biomembranes for synthetic biology
- Membrane proteins in drug targeting and antimicrobial resistance
Awards & Grants
Recipient of prestigious awards including the Royal Society Wolfson Merit Award and Philip Leverhulme Prize. Funded by grants from Wellcome Trust, ERC, BBSRC, and EPSRC, among others.
Advising & Grants
- Supervised Students: Marvin Dilworth, Heather Findlay, Juan Palacios-Ortego, Benjamin Russell Lewis, Erin Johnston, Kaylee Patel, Wenjuan Sun
- Active Projects: RiboForce (BBSRC), HumanCF (Leverhulme Trust), and collaborations on cryo-electron microscopy (BBSRC)
Labs & Teams
The Booth Group operates at King's College and the Francis Crick Institute, focusing on membrane protein biogenesis, synthetic biology applications, and interdisciplinary methods like droplet interface bilayers.
