Olga B. Ioffe

Olga B. Ioffe, MD is Professor of Pathology at the University of Maryland School of Medicine, where she also serves as Vice Chair for Education & Faculty Development and Director of the Pathology and Biorepository Shared Service at the University of Maryland Marlene and Stewart Greenebaum Cancer Center. She is an attending staff pathologist at University of Maryland Hospital, specializing in surgical pathology and cytopathology with particular expertise in breast and gynecologic pathology.

Education and Training

• MD – Moscow State Medical Institute, Moscow, Russia
• Residency in Internal Medicine – Greater Baltimore Medical Center
• Residency in Anatomic and Clinical Pathology – University of Maryland School of Medicine
• Fellowship in Surgical Pathology (Breast & Gynecologic Pathology) – University of Maryland School of Medicine

Research Interests

Dr. Ioffe’s research centers on surgical pathology, breast pathology, and gynecologic pathology. She investigates breast cancer and premalignant breast disease, focusing on diagnostic accuracy and prognostic factors. Her work spans biomarker discovery, translational studies, and the integration of imaging modalities with pathologic assessment. She leads the institutional tissue bank and serves as central pathologist for major NIH and cooperative group studies.

Publications Trend

Her recent publications (2002-2016) demonstrate sustained productivity in breast and gynecologic pathology, with emphasis on prognostic biomarkers such as GP88/progranulin, risk-stratification tools like the Nottingham Prognostic Index, and large-scale epidemiologic studies validating long-term cancer risk following endometrial hyperplasia. Additional work addresses diagnostic reproducibility in endocervical glandular lesions and multimodal imaging-pathology correlation for breast cancer staging.

Roles & Collaborations

• Director, Pathology and Biorepository Shared Service, UM Greenebaum Cancer Center
• Central reviewing pathologist for NIH Resource for Collection and Evaluation of Human Tissues and Cells
• Referee pathologist for Gynecologic Oncology Group, CALGB, and The Cancer Genome Atlas Biospecimen Core Resource
• Editor-in-Chief, American Journal of Surgical Pathology: Reviews and Reports

Laboratory & Team Leadership

As Director of the Pathology and Biorepository Shared Service, Dr. Ioffe oversees a comprehensive institutional tissue bank that supports translational research across multiple cancer types. Her team provides diagnostic confirmation and classification services for national cooperative groups and large-scale genomic initiatives.