Charles Zaloudek

Charles Zaloudek, MD is a Professor in the Department of Pathology at the University of California San Francisco (UCSF) School of Medicine, specializing in gynecologic and surgical pathology. His extensive career spans over five decades with continuous scholarly contributions to diagnostic pathology and molecular oncology.

Education:

• University of California, Berkeley: A.B. (1967)
• Johns Hopkins School of Medicine: M.D. in Medicine (1971)
• Stanford University: Pathology Residency (1971-73)
• Stanford University: Surgical Pathology Fellowship (1973-74)

Dr. Zaloudek's research focuses on gynecologic pathology, particularly uterine and ovarian tumors, molecular diagnostics, and classification systems for endometrial carcinoma. His work integrates morphologic analysis with genomic profiling to establish diagnostic criteria and prognostic models. Current research emphasizes inflammatory myofibroblastic tumors, hereditary cancer syndromes (like HLRCC), and molecular signatures in gynecologic malignancies.

Analysis of his recent publications reveals a strong trend toward integrated clinicopathologic-molecular approaches, with emphasis on risk stratification models (2023), diagnostic pitfalls in p53 immunohistochemistry (2021), and mutation-driven tumor classification (CTNNB1, TRAF7, FH). His collaborative work with the International Society of Gynecologic Pathologists has established critical diagnostic standards for endometrial carcinoma processing and prognostication.

Professional Contributions:

• Co-author of landmark guidelines for endometrial carcinoma grossing and processing (2019)
• Key contributor to understanding hereditary leiomyomatosis and renal cell carcinoma syndrome
• Significant research on peritoneal mesothelioma genetics and uterine tumor classification

Dr. Zaloudek maintains active collaborations with UCSF's Helen Diller Family Comprehensive Cancer Center, particularly in molecular tumor boards and diagnostic pathology consultations. His work bridges basic science discoveries with clinical diagnostic applications, significantly influencing gynecologic pathology practice standards worldwide.