معرفی
Nora Barrett, MD, is an Associate Professor of Medicine at Harvard Medical School and an attending physician at Brigham and Women’s Hospital, where she leads the Respiratory Immunology Laboratory. She also serves as Director of Research Training for the Allergy and Immunology fellowship program. Her federally funded research deciphers innate immune signaling in the respiratory tract, with a focus on type 2 inflammatory diseases such as asthma and chronic rhinosinusitis with nasal polyps.
Education & Training
- MD earned (institution/year not specified in text)
- Clinical and research fellowship training in Allergy & Immunology (details not provided)
Research Focus
The Barrett Lab integrates in vivo murine models, single-cell RNA-sequencing of human tissues, and molecular immunology to uncover how environmental exposures trigger innate immune cascades. A long-standing theme is the role of cysteinyl leukotrienes (CysLTs) as amplifiers of innate sensing. More recently, the lab has uncovered genetic and epigenetic programs that drive airway epithelial remodeling, altering mucosal barrier function and immune homeostasis.
Scientific Awards & Honors
- Joshua A. Boyce, MD Distinguished Chair in Allergy and Clinical Immunology (2022)
- Elected to the American Society for Clinical Investigation (ASCI) – induction April 2023
Grants & Funding
While specific grant numbers are not listed, the lab’s continuous productivity and the 2025 commentary on the crucial impact of NIH funding indicate substantial federal support, likely from NHLBI and NIAID.
Laboratory & Team
The Respiratory Immunology Lab is housed in the Hale Building for Transformative Medicine (Room 05002R) at Brigham and Women’s Hospital. The group comprises post-doctoral fellows, graduate students, research technicians, and clinical fellows who meet regularly for lab outings and scientific retreats, fostering a collaborative training environment.
