Nikolaus Falb

Nikolaus Falb is a researcher at the Institute of Biochemistry, University of Natural Resources and Life Sciences, Vienna (BOKU). His work focuses on structural and functional analysis of enzymes in microbial systems, particularly in actinobacterial ChdC and heme biosynthesis pathways.

• Primary Affiliation: Institute of Biochemistry, BOKU
• Email: nikolaus.falb@boku.ac.at

Research Interests

Falb investigates biochemical mechanisms in microbial enzymes, including

• pH-dependent reactivity in chlorite dismutase
• Structural dynamics of catalytic arginine residues
• Heme biosynthesis in Gram-positive bacteria
• Computational modeling of protein interactions

Publications

His recent work explores enzyme structure-function relationships in Actinobacteria, with two 2023 publications focusing on

• Chlorite dismutase catalytic mechanisms
• Structural insights into prokaryotic heme biosynthesis enzymes

Projects

Actively contributes to In-depth studies of actinobacterial ChdC (FWF-funded, 2021-2025), a project analyzing enzyme dynamics in dimeric systems.