معرفی
Dr Nik Hodges is a Reader in Toxicology at the School of Biosciences, University of Birmingham. His research focuses on genetic toxicology, cellular oxidative stress, and DNA repair mechanisms. He is a lecturer on undergraduate and postgraduate toxicology modules, including the MSc/MRes programs, and serves as course director for the MRes Molecular Mechanistic Toxicology. His lab pioneered studies on the OGG1 protein's repair deficiency under oxidative stress, with implications for cancer susceptibility.
Education: BSc and MSc in Biochemistry and Toxicology from the University of Nottingham, followed by a PhD in Toxicology under Prof. Kevin Chipman. Postdoctoral roles included occupational health research on hexavalent chromium and AstraZeneca-funded work on secondary genotoxicity.
Research Interests: Mechanisms of OGG1 dysfunction during oxidative stress; cytoglobin's role in fibrosis and drug toxicity; iron cylinder cytostatic effects; nanoparticle toxicity. Collaborations include AstraZeneca (cytoglobin-fibrosis) and Professors Hannon/Chipman (iron cylinders).
Publications emphasize DNA repair pathways, oxidative stress responses, and nanomaterial interactions. Consultancies include Monsanto, VetXX, and DFID for toxicological risk assessments. No explicit awards listed, but his work has advanced understanding of genetic and environmental toxicity links.
Labs/Teams: Lead the Hodges Lab within School of Biosciences, specializing in redox biology and toxicological mechanisms. Collaborates across disciplines to address environmental and medical toxicology challenges.
