معرفی
Nicolas Noiseux is a tenured Full Professor in the Department of Surgery at the University of Montreal, Canada, and Director of Cardiovascular Research at the CHUM (Centre Hospitalier de l’Université de Montréal). He is a cardiac surgeon with expertise in regenerative medicine, stem cell therapy, and organ transplantation. Dr. Noiseux leads a translational research program focused on improving outcomes for patients with ischemic cardiovascular diseases and advancing organ perfusion techniques. He has pioneered clinical trials such as the COMPARE-AMI and IMPACT-CABG studies, which explored the use of CD133+ stem cells for treating heart failure. His surgical innovations include a novel anterolateral coronary bypass strategy and the implementation of ex vivo lung perfusion programs to expand transplant donor eligibility.
Education:
- BSc in Biochemistry, Université Laval (1989–1992)
- MSc in Molecular Biology, Université Laval (1991–1993)
- MD, Université Laval (1992–1996)
- Fellowship in Cardiac Surgery, Université de Montréal (1996–2002)
- Postdoctoral Research Fellowship in Regenerative Medicine, Harvard Medical School (2002–2005)
Research Interests:
Dr. Noiseux’s work spans clinical, translational, and preclinical studies. Key areas include:
- Stem cell therapy for ischemic heart disease
- Ex vivo organ perfusion systems for heart, lungs, and kidneys
- Novel pharmacological agents to mitigate ischemia-reperfusion injury
- Advanced surgical techniques for complex cardiac cases
- Large-animal models of cardiovascular pathologies
Grants & Awards:
- Senior Clinical Research Fellow, FRQS (2016–present)
- Co-founder and Chief Medical Officer of Targa Biomedical
- Honorary Colonel of Kentucky (2018)
- King Charles III Coronation Medal (2025)
Labs & Teams:
He directs the Ex vivo Perfusion Program at CHUM and collaborates with the ThéCell Network for Cell and Tissue Therapy. His lab develops pharmacological and engineering solutions to enhance organ viability and therapeutic efficacy in transplantation and regenerative medicine.
