Nicholas A Cacalano

Nicholas A Cacalano is an Associate Professor in Radiation Oncology at the University of California Los Angeles (UCLA) School of Medicine. His research focuses on the interplay between natural killer (NK) cells and cancer progression, particularly in prostate cancer, glioblastoma, and oral tumors.

• Key Research Areas: Immunology, Cancer Biology, Radiation Oncology, Stem Cell Research, Molecular Biology, Cell Signaling
• Collaborations: Frequent co-authorship with researchers like A. Jewett, C. Jamieson, and C. Kane

His work explores mechanisms such as NK cell-mediated targeting of cancer stem cells, SOCS protein regulation in immune responses, and resistance to radiotherapy. Recent publications highlight advancements in 3D organoid models and immunotherapeutic strategies for pancreatic and prostate cancers.

Publications (2003–2022) demonstrate interdisciplinary contributions to Molecular Biology, Immunology, and Oncology, with subfields including Tumor Microenvironment, Epigenetic Regulation, and Immune Evasion. His studies often involve cell-based models, animal xenografts, and cytokine signaling.

Current affiliations and projects are centered at UCLA, with a focus on translational research bridging molecular mechanisms and clinical applications in oncology.