معرفی
Dr. Natalie Lister is a Research Fellow in the Department of Anatomy & Developmental Biology at Monash University, specializing in prostate cancer research. She leads the Prostate Cancer Group focused on developing targeted therapies for drug-resistant prostate cancers. Her research integrates computational network modeling with preclinical models (patient-derived xenografts/organoids) to identify actionable therapeutic vulnerabilities in aggressive tumors.
- Affiliations: Monash Medical Centre (Scientific Advisory Committee), Monash University (Steering Committee - BDI Organoid Platform)
- Key Projects: FLPF 2023 Fellowship, Targeted Reprogramming of Prostate Cancer, PSMA Theranostics Alliance
Research interests center on tumor microenvironment dynamics, transcriptional networks driving malignancy, and novel drug discovery strategies. She has pioneered over 30 patient-derived prostate cancer models to bridge preclinical/clinical research gaps.
Highlights include:
- Identified SAMD14 as a mast cell-regulated microenvironment modifier
- Discovered LOXL2-dependent fibroblast signaling pathways
- Developed CAR T-cell therapies enhanced by carboplatin preconditioning
Awards: Monash Biomedicine Pitch Competition (2019), Australian Postgraduate Award (2007), and multiple institutional scholarships.
Teaching: Tutor for Immunology 3031; guest lectures on translational oncology. Engages in STEM outreach through Girls Day Australia and patient education initiatives.
