معرفی
Dr. Min Shin is a Research Scientist in Rheumatology at Yale School of Medicine, focusing on immune system mechanisms in immune deficiency and dysregulation. She holds a PhD from Catholic University of Korea, School of Medicine (2002). Her research uses advanced immune profiling to study T cell dysfunction, cytokine signaling pathways, and aging-related immune alterations. Key areas include CD8+ T cell heterogeneity, IL-7 receptor expression dynamics, and vaccine responses in aging populations. Collaborating with Dr. Insoo Kang's lab, her work bridges genetic defects, clinical phenotypes, and immune biomarkers in disorders like 17q12 deletion syndrome. Recent studies highlight T helper 1 cell defects in sinopulmonary infections and IL-1 receptor modulation in mRNA vaccine efficacy.
- Affiliations: Rheumatology Research, Yale School of Medicine
- Education: PhD in Immunology from Catholic University of Korea
Research interests emphasize translational immunology with a focus on immune biomarkers for diagnostic and therapeutic applications. Her work spans from genetic immunodeficiency studies to inflammatory disease mechanisms, including contributions to understanding SARS-CoV-2 immune responses.
Publications highlight interdisciplinary approaches, combining single-cell sequencing, transcriptomics, and clinical data to elucidate immune aging and vaccine immunogenicity. Ongoing projects investigate biomarkers linking T cell senescence to neurocognitive decline in Alzheimer’s patients and cytokine signaling pathways in vaccine efficacy.