Melike Lakadamyali

Melike Lakadamyali is a Professor at the Perelman School of Medicine, University of Pennsylvania, with secondary appointments in Cell and Developmental Biology. Her research focuses on biophysics, super-resolution microscopy, and macromolecular assembly dynamics in cellular processes.

• Education: BS (2001) from University of Texas at Austin, PhD (2006) from Harvard University

Her work aims to understand the spatiotemporal organization of cellular machinery through advanced single-molecule imaging and quantitative models. Key projects include vesicle transport, transcriptional regulation, and chromatin plasticity.

Recent publications highlight methodological innovations like ECLiPSE classification and MiOS imaging-computational strategies. Articles span nucleosome dynamics, mitochondrial fission, and microtubule regulation, emphasizing biophysical quantification.

• Scientific Awards: EMBO Young Investigator (2013), Ramon y Cajal Fellowship (2014), Hans Fisher Junior Fellow (2016), La Vanguardia Finalist (2016)

She advises a research team developing super-resolution tools for vesicular trafficking and chromatin studies, with advisory roles on Bruker/Vutara and BioQuant boards. Her lab employs quantitative approaches to study macromolecular complexes in cellular homeostasis and disease mechanisms.