Marion Chan

Dr. Marion Chan is an Associate Professor at the Lewis Katz School of Medicine, Temple University, where she investigates mechanisms of inflammation resolution and their implications in autoimmune diseases, parasitic infections, and cancer. Her research integrates Biomedical Education and Data Science with Microbiology, Immunology, and Inflammation.

• Education: PhD from Cornell University Medical College

Her work focuses on:

• Elucidating active inflammation-resolution mechanisms in collagen-induced arthritis and Leishmania infection
• Exploring roles of PPARγ in macrophage polarization and disease progression
• Assessing dietary phytochemicals (e.g., curcumin, epigallocatechin-3-gallate) as modulators of cancer stem cells and inflammatory pathways

Recent publications highlight her expertise in:

• PPARγ-mediated immune responses
• Neuroinflammatory aspects of rheumatoid arthritis
• Phytochemicals in drug resistance and parasitic infections
• Inflammation-resolution pathways in autoimmune and neoplastic diseases

She has contributed extensively to understanding how bioactive lipids and COX/LOX pathways interact with nuclear receptors to influence disease outcomes, with a particular focus on M1/M2 macrophage dynamics and apoptotic cell clearance.