Manu Sharma

Manu Sharma, MD is an Assistant Clinical Professor of Psychiatry at Yale School of Medicine (Yale University). He serves as Unit Chief of the Inpatient Psychosis Unit at Yale New Haven Psychiatric Hospital, focusing on developing digital health tools to improve care for individuals with chronic and serious mental illnesses. His research interests include digital psychiatry innovations, anti-inflammatory interventions in schizophrenia, and biomarker discovery in mental health.

Sharma’s academic contributions span neuroimaging, systemic reviews of treatment efficacy, and clinical challenges in psychiatric diagnosis. Notable work includes studies on resting-state functional connectivity in schizophrenia, inflammatory markers in bipolar disorder, and neuromodulation for treatment-resistant depression. He has been recognized with an appointment to the American Psychiatric Association (APA) Committee on Innovation, focusing on digital health advancements.

His clinical expertise bridges inpatient care and academic research, emphasizing translational medicine. Ongoing projects explore real-world task ambiguity in mental healthcare and the role of anti-inflammatory therapies in metabolic syndrome comorbidities. Sharma’s work aims to integrate technology-driven solutions into standard psychiatric practices while addressing systemic gaps in patient care.