معرفی
Man Shrestha is an Associate Research Scientist in the Department of Comparative Medicine at Yale School of Medicine (Yale University). His research focuses on adipokine signaling (e.g., adiponectin and resistin), glucose homeostasis, and metabolic disorders such as polycystic ovary syndrome (PCOS) and obesity. He employs advanced techniques like real-time TIRF microscopy and proteomics to study adipocyte exocytosis, skeletal muscle metabolism, and placental nutrient transport mechanisms.
Key contributions include elucidating the role of adiponectin in placental function, AMPK-mediated glucose transport regulation, and the pathophysiological changes in PCOS-affected muscle tissue. His work bridges cell biology with clinical endocrinology, emphasizing translational implications for metabolic diseases.
Shrestha collaborates across departments within Yale School of Medicine, focusing on interdisciplinary projects involving reproductive biology, developmental biology, and molecular physiology. His recent studies highlight disturbed adrenergic signaling in obesity and the interplay between actin cytoskeleton dynamics and metabolic pathways.
