معرفی
Luisa Cochella is an Assistant Professor in the Department of Molecular Biology and Genetics at the Johns Hopkins University School of Medicine. Her research focuses on the molecular mechanisms that generate neuronal diversity during development and evolution, using the nematode C. elegans as a primary model system.
Her research interests include:
- Transcriptional and post-transcriptional regulation in neuronal development
- Temporal and spatial combinatorial control by transcription factors
- Role of microRNAs in neuronal specialization and sensory function
- Chromatin dynamics and gene expression memory
- Evolution of gene regulatory networks in the nervous system
Dr. Cochella's lab develops and applies innovative molecular tools such as mime-seq to profile miRNA expression at single-cell resolution. Her work bridges developmental biology, neuroscience, and molecular genetics to uncover fundamental principles of cellular differentiation.
Her recent publications reveal trends in understanding how gene regulatory mechanisms—both transcriptional and post-transcriptional—contribute to neuronal identity and function. These studies employ genetic, biochemical, and genomic approaches to dissect mechanisms conserved across species.
Dr. Cochella is affiliated with the Neuroscience Training Program and mentors graduate students. She leads an active research laboratory focused on gene regulation in neural development.
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