Lucy Mary Golden

Lucy Mary Golden, PhD, is a Clinical Professor at the University of Southern California (USC), specializing in hepatology and immunology with a focus on liver diseases, viral hepatitis, and immune mechanisms. Her research explores the interplay between viral infections, immune responses, and hepatic pathogenesis, particularly in hepatitis C virus (HCV) and non-alcoholic fatty liver disease (NAFLD/NASH). Key areas include NK cell biology, cytokine networks, and therapeutic intervention strategies.

Her work investigates how innate immune cells (e.g., natural killer cells, macrophages) regulate liver inflammation and fibrosis. Recent studies highlight the role of autophagy in CD11c+ cells, cholesterol metabolism in steatosis, and exosome-mediated immune modulation in HCV infection. She has also examined environmental factors like mercury exposure and dietary lipids in liver injury progression.

Dr. Golden’s publications span over two decades, reflecting her expertise in viral hepatitis, immune evasion mechanisms, and translational hepatology. Her work bridges basic science and clinical applications, aiming to improve diagnostic tools and antiviral therapies.

Her research has contributed to understanding the role of galectin-9 in immune regulation, the impact of direct-acting antivirals on HCV patients’ T cells, and the pathophysiology of liver injury in pediatric and adult populations. While no specific grants or student names are listed here, her extensive publication record underscores her leadership in liver immunology research.