Salim I. Khakoo

Professor Salim I. Khakoo is a faculty member at the University of Southampton, affiliated with the Medical School and the Department of Hepatology. His research focuses on immunology, particularly the mechanisms of natural killer (NK) cell activation and their interactions with KIR receptors and HLA molecules in the context of viral infections.

His research explores the role of genetic loci in immune responses, with a focus on hepatitis C virus (HCV) clearance, receptor-ligand dynamics, and the impact of cytokines like IL-12 and IL-15 on NK cell function.

Key trends in his publications (2013–2020) revolve around immunology, genetics, and hepatology, with subfields including KIR receptor polymorphism, HLA-C binding, peptide antagonism, and genetic associations in viral immunity. Notably, his work on MHC class I deficiency and NK cell repertoire formation highlights the complexity of immune system interactions.