Lucie Carrier

Lucie Carrier is a Professor at the Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf. She leads a research group focusing on cardiomyopathy mechanisms, particularly involving sarcomere proteins like cardiac myosin-binding protein C (MyBP-C) and their role in hypertrophic cardiomyopathy (HCM). Her work explores ubiquitin-proteasome system dysfunction, autophagy, and gene therapy approaches for HCM. Key collaborators include Thomas Eschenhagen and Sandra Schlossarek.

• Research Interests: Sarcomere mutations, proteasome inhibition, RNA editing, cardiac remodeling, iPSC models, and microRNA regulation in HCM.
• Grants & Projects: Multiple studies on Mybpc3-targeted mouse models, iPSC-derived cardiomyocytes, and pharmacological interventions (e.g., nebivolol, sacubitril/valsartan).
• Key Contributions: Discoveries about MyBP-C phosphorylation, ANKRD1 mutations, and tubulin detyrosination as therapeutic targets. She co-authored guidelines for autophagy assays and ESC consensus documents.
• Scientific Awards: No explicit awards mentioned in the text.